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This question tests the proper use of punctuation when connecting a non-essential element and a main clause.

Choice A) is incorrect. The colon incorrectly suggests that the information after the colon is an explanation or amplification of the information in the non-essential element, which isn't the case.

Choice B) is incorrect because it lacks the necessary punctuation to link the non-essential element with the main clause, resulting in a run-on sentence.

Choice C) is the correct answer. It uses a comma to correctly link the non-essential element "An architect ... iconic skyscrapers" with the main clause "James Thompson was invited to speak at the Global Design Summit."

Choice D) is incorrect. A semicolon can't be used in this way to join the non-essential element and the main clause. Semicolons are conventionally used to separate two main clauses or to separate items in a complex series, neither of which applies here.